Rheumatoid arthritis – a systemic disease of connective tissue, mainly affecting small joints of the type of erosive and destructive polyarthritis of unknown etiology with a complex autoimmune pathogenesis.
Causes of the disease on this day are unknown. Indirect data, such as increasing the number of white blood cell count and erythrocyte sedimentation rate (ESR) indicate the infectious nature of the process. It is believed that the disease develops as a result of infection, which causes a compromised immune system in genetically susceptible individuals, with formation of so-called. immune complexes (of the antibodies, viruses, etc..), which are deposited in tissues and lead to joint damage. But the ineffectiveness of antibiotic treatment of RA is likely to indicate the incorrectness of this assumption.
